The Laboratory of Cell Toxicology is located in the Center of Biological Sciences, Federal University of Parana, Brazil. The laboratory was created in 1997 by Ciro Alberto de Oliveira Ribeiro and Marco Antonio Ferreira Randi, at a time when financial resources of Brazilian agencies for the establishment of new research lines were scarce. In the very beginning, the laboratory occupied two separate spaces, one dedicated to bioassays and the other for preparation and analysis of biological samples. The first improvements in this original physical structure came from resources obtained through a research work performed for a North American Company by the AQUATOXI Research Group, which has been created at that time.

In the first years, the Laboratory of Cell Toxicology had the support of the Marine Toxicology Laboratory (Institut des Sciences de la Mer at Université du Québec à Rimouski – Canada), through scientific collaboration with Mr. Émilien Pelletier. This support was essential, since there were few calls for proposals of Brazilian research agencies available and the policy for science and technology has greatly favored well-established research groups at that time.
From those years until now, the laboratory has expanded in infrastructure, experience and knowledge in the fields of ecotoxicology, environmental toxicology and cellular mechanisms of response to chemical stress.
Now, The Laboratory of Cell Toxicology  is a reference in the area of Cell Toxicology with several national and international collaborations. The current research staff consists of five professors with PhD degrees, postdoctoral scholars and undergraduate and post graduation students.